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Michael H. Creer, M.D.

Professor and Chief of Clinical Pathology Director, Clinical Laboratory Medical Co-Director, Special Hematology and Hemostasis and Thrombosis Laboratories

Office Information

Penn State Hershey Clinical Pathology
500 University Drive
Hershey, PA 17033-0850
Tel: 800-243-1455 / 717-531-8615 Fax: 717-531-3803


Clinical Pathology

Patient Services Provided

General Clinical Pathology Hemostasis Hematology Transfusion Medicine Hematopoietic Cell Therapy

Biographical Information

Born in Spanish Fork, Utah
Married:  Wife - Tracy (Attorney at Law); Son - Harry

Professional Education

Residency, Clinical Pathology, Washington Univ., Barnes-Jewish Hospital (1983) M.D., University of Utah, School of Medicine (1980)

Research Interests

Basic Research:  Protease-activated receptors (PAR) and novel phospholipases in platelet and endothelial cell signal transduction, PAR-mediated alterations in adhesion molecule expression and adaptive mechanisms employed by hematopoietic stem/progenitor cells for survival in hypoxic environments.

Translational Research:  Automated hematology analysis of hematopoietic stem/progenitor cells and engraftment analysis following hematopoietic cell therapy, clinical laboratory approaches to assess platelet function in vivo and in vitro.

Academic Interests

Stem Cell Biology, Biology of Coagulation Proteases and Signal Transduction Mechanisms Regulating Platelet Function


Hess DA, Craft TP, Wirthlin L, Hohm S, Zhou P, Eades WC, Creer MH, Sands MS, Nolta JA
Widespread Nonhematopoietic Tissue Distribution by Transplanted Human Progenitor Cells with High Aldehyde Dehydrogenase Activity
Stem Cells 26:611-620, 2008
Sharma J, Rastogi P, Creer M, McHowat J
Polymorphonuclear leukocytes isolated from Umbilical Cord Blood as a Useful Research Tool to Study Inflammation
Journal of Immunological Methods 351:30–35, 2009
Solomon M, Wooford J, Johnson C, Regan D, Creer MH
Factors Influencing Cord Blood Viability Assessment Before Cryopreservation
Transfusion 50:820-830, 2010
Sondergaard CS, Hess DA, Maxwell DJ, Weinheimer C, Rosova I, Creer MH, Piwnica-Worms D, Kovacs A, Pederson L, Nolta JA
Human cord blood progenitors with high aldehyde dehydrogenase activity improve vascular density in a model of acute myocardial infarction
J Transl Med 8(1):24-32, Mar 9 2011. [Epub ahead of print]PMID: 20214792 [PubMed - as supplied by publisher]
Kudva G, Vadivel K, Rassi V, Caracioni A, Crown H, Reimers HJ, Creer MH, Bajaj SP
Mutation Analysis for Overcoming Difficulty in Diagnosing Mild Hemophilia A
Hemophilia (under review)
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