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J Stanley Smith, Jr., M.D.

Office Information

Penn State Hershey Breast Center
30 Hope Drive, Building A, Suite 1800
Hershey, PA 17033
Tel: 800-243-1455 / 717-531-5867 Fax: 717-531-2041


Breast Surgery General Surgery Surgical Oncology

Patient Services Provided

Breast Cancer Breast Ultrasound Breast Diseases Breast Intervention

Practice Locations

Professional Education

Fellowship, Traumatology, University of Maryland Medical System (1976) Residency, Surgery, General, PinnacleHealth System-Polyclinic Medical Center (1975) M.D., Jefferson Medical College (1971)

Research Interests

  • Breast Cancer
  • Cryotherapy


Kaufman CS, Littrup PJ, Freeman-Gibb LA, Smith JS, Francescatti D, Simmons R, Stocks LH, Bailey L, Harness JK, Bachman BA, Henry CA.
Office-based Cryoablation of Breast fibroadenomas with Long-term Follow-up.
The Breast Journal 2005; 11:344-350.
Planas-Silva MD, Bruggeman RD, Grenko RT, Smith JS.
Role of c-Src and focal adhesion kinase in progression and metastasis of estrogen receptor positive breast cancer.
Biochem Biophys Research Commun 2006; 341:73-81.
Tafra L, Fine R, Whitworth P, Berry M, Woods J, Ekbom G, Gass J, Beitsch P, Dodge D, Han L, Potruch T, Francescatti D, Oetting L, Smith JS, Snider H, Kleban D, Chagpar A, Akbari S.
Prospective randomized study comparing cryo-assisted and needle-wire localization of ultrasound-visible breast tumors.
Am J Surg. 2006; 192(4):462-70.
Planas-Silva MD, Bruggeman RD, Grenko RT, Smith JS.
Overexpression of c-Myc and Bcl-2 during progression and distant metastasis of hormone-treated breast cancer.
Exp Mol Pathol. 2006 Oct 12.
Smith JS, Frankenfield DC.
In Surgery: Scientific Principles and Practice, 5th edition, Mulholland MW, Lillemoe KD, Doherty GM, Maier RV, Upchurch GR eds.,  Philadelphia, Lippincott Williams and Wilkins, 2010.

Honors and Awards

Thomas V. N. Ballantine Memorial Excellence in Surgical Education Award (June 2000) America's Top Surgeons, Consumers' Research Council of America (2002-2009)