Bioengineering - Publications

Peer-Reviewed Publications


  1. Siedlecki CA, Eppell SJ, and Marchant RE. "Interactions of Human von Willebrand Factor with a Hydrophobic Self-Assembled Monolayer Studied by Atomic Force Microscopy". Journal of Biomedical Materials Research 28: 971-980 (1994).
  2. Siedlecki CA, Lestini BJ, Kottke-Marchant K, Eppell SJ, Wilson DL, and Marchant RE. "Shear Dependent Changes in the Three Dimensional Structure of Human von Willebrand Factor". Blood 88: 1239-1250 (1996).
  3. Baty A, Leavitt P, Siedlecki CA, Tyler, B, Suci P, Marchant RE, and Geesey G. "The adsorption of adhesive proteins from the marine mussel, Mytilus Edulis, on polymer films in the hydrated state using angle dependent XPS and AFM". Langmuir 13: 5702-5710 (1997).
  4. Marchant RE, Shainoff BJ, Eppell SJ, Wilson DL and Siedlecki CA. "Three dimensional structure of human fibrinogen under aqueous conditions visualized by atomic force microscopy". Thrombosis and Haemostasis 77: 1048-1051 (1997).
  5. Siedlecki CA and Marchant RE. "Atomic force microscopy for characterization of the biomaterial interface". Biomaterials 19: 441-454 (1998).
  6. Holland NB, Siedlecki CA, Marchant RE. "Intermolecular Force Mapping of Platelet Surfaces on Collagen Substrata". Journal of Biomedical Materials Research 45: 167-174 (1999).
  7. Siedlecki CA, Wang I-w, Higashi JM, Kottke-Marchant K and Marchant RE. "Platelet-Derived Microparticles on Synthetic Surfaces Observed by Atomic Force Microscopy and Fluorescence Microscopy". Biomaterials 20: 1521-1529 (1999).

  8. Garrett JT, Siedlecki CA, Runt JP. "Microdomain Morpholology of Poly(urethane urea) Multiblock Copolymers". Macromolecules 34: 7066-7070 (2001).
  9. Krishnan A., Siedlecki CA, Vogler EA. "A Traube-Rule Interpretation of Protein Adsorption at the Liquid Vapor Interface". Langmuir 19: 10342-10352). (2003)

  10. Krishnan A, Sturgeon J, Siedlecki CA, Vogler EA. "Scaled Interfacial Activity of Proteins at the Liquid-Vapor Interface". Journal of Biomedical Materials Research 68A: 544-557 (2004).
  11. Hussain MA, Siedlecki CA. "The platelet integrin alpha(IIb) beta(3) imaged by atomic force microscopy on model surfaces". Micron 35: 565-573 (2004).
  12. Milner KR, Balmer M, Donahue HJ, Snyder AJ, Siedlecki CA. "Fabrication of Ordered Sub-Micron Topographies on Large Area Poly(Urethane Urea) by Two-Stage Replication Molding". Materials Research Society Symposium Proceedings 820: R2.8.1-R2.8.6 (2004).
  13. Krishnan A., Siedlecki CA, Vogler EA. "Mixology of Protein Solutions and the Vroman Effect. Langmuir 20: 5071-5078 (2004).
  14. Agnihotri A, Siedlecki CA. "Time-Dependent Conformational Changes in Fibrinogen Measured by Atomic Force Microscopy". Langmuir 20: 8846-8852 (2004).

  15. Zhuo R, Miller R, Bussard KM, Siedlecki CA, Vogler EA. "Procoagulant Stimulus Processing by the Intrinsic Pathway of Blood Plasma Coagulation". Biomaterials 26: 2965-2973 (2005).
  16. Krishnan A, Wilson A, Sturgeon J, Siedlecki CA, Vogler EA. "Liquid-Vapor Interfacial Tension of Blood Plasma, Serum and Purified Protein Constituents Thereof". Biomaterials 26: 3445-3453 (2005).
  17. Agnihotri A, Siedlecki CA. "Adhesion Mode Atomic Force Microscopy Study of Dual Component Protein Films". Ultramicroscopy 102: 257-268 (2005).
  18. Lim JY, Hansen JC, Siedlecki CA, Runt JP, Donahue HJ. "Human Fetal Osteoblastic Cell Response to Polymer-Demixed Nanotopographic Interfaces". J of the Royal Society, Interface 2: 97-108 (2005).
  19. Hussain MA, Agnihotri A, Siedlecki CA. "AFM Imaging of Ligand Binding to Platelet Integrin aIIbß3 Receptors Reconstituted into Planar Lipid Bilayers". Langmuir 21: 6979-6986 (2005).
  20. Yamanaka H, Rosenberg G, Weiss WJ, Snyder AJ, Zapanta CM, Siedlecki CA. "Multiscale Analysis of Thrombosis in Left Ventricular Assist Systems". ASAIO Journal 51: 567-577 (2005).
  21. Milner KR, Siedlecki CA, Snyder AJ. "Development of Novel Sub-Micron Textured Polyether(Urethane Urea) for Decreasing Platelet Adhesion". ASAIO Journal 51: 578-584 (2005).
  22. Lim JY, Hansen JC, Siedlecki CA, Hengstebeck B, Cheng J, Winograd N, Donahue HJ. "Osteoblast Adhesion on Poly(L-lactic acid)/Polystyrene Demixed Thin Film Blends: Effect of Nanotopography, Surface Chemistry, and Wettability". Biomacromolecules 6: 3319-3327 (2005).

  23. Miller R, Guo Z, Vogler EA, Siedlecki CA. "Plasma Coagulation Response to Surfaces with Nanoscale Chemical Heterogeneity". Biomaterials. 27: 208-215 (2006).
  24. Guo Z, Bussard KM, Chatterjee K, Miller R, Vogler EA, Siedlecki CA. "Mathematical Modeling of Material-Induced Blood Plasma Coagulation". Biomaterials 27: 796-806 (2006).
  25. Agnihotri A, Garrett JT, Runt J, Siedlecki CA. "Atomic Force Microscopy Visualization of Poly(urethane urea) Microphase Rearrangements under Aqueous Conditions ". Journal of Biomaterials Science-Polymer Edition 17: 227-238 (2006).
  26. Milner KR, Snyder AJ, Siedlecki CA. "Sub-Micron Texturing for Reducing Platelet Adhesion to Polyurethane Biomaterials". Journal of Biomedical Materials Research A 76: 561-570 (2006).
  27. Yamanaka H, Rosenberg G, Weiss WJ, Snyder AJ, Zapanta CM, Siedlecki CA. "Short-term In Vivo Studies of Surface Thrombosis in a Left Ventricular Assist System". ASAIO Journal 52: 257-265 (2006).
  28. Zhuo R, Siedlecki CA, Vogler EA. "Auto-activation of Blood Factor XII at Hydrophilic and Hydrophobic Surfaces". Biomaterials, 27: 4325-4332 (2006).
  29. Chatterjee K, Vogler EA, Siedlecki CA. "Procoagulant Activity of Surface-Immobilized Hageman Factor". Biomaterials 27: 5643-5650 (2006).

  30. Lim JY, Dreiss AD, Zhuo Z, Hansen JC, Siedlecki CA, Hengstebeck RW, Cheng J, Winograd N, Donahue HJ. "The Regulation of Integrin Mediated Osteoblast Focal Adhesion and Focal Adhesion Kinase Expression by Nanoscale Topography". Biomaterials 28: 1787-1797 (2007).
  31. Xu LC, Soman P, Runt J, Siedlecki CA. "Characterization of Surface Microphase Structures of Poly(urethane urea) Biomaterials by Nanoscale Indentation with AFM". Journal of Biomaterials Science Polymer Edition 18: 353-368 (2007).
  32. Milner KR, Siedlecki CA. "Submicron Poly(L-Lactic Acid) Pillars Affect Fibroblast Adhesion and Proliferation. Journal of Biomedical Materials Research A 82A: 80-91 (2007).
  33. Xu LC, Siedlecki CA. "Effect of Surface Wettability and Contact Time on Protein Adhesion to Biomaterial Surfaces". Biomaterials 28, 3273-3283 (2007).
  34. Milner KR, Siedlecki CA. "Fibroblast Response is Enhanced by Poly(L-Lactic Acid) Nanotopography Edge Density and Proximity." International Journal of Nanomedicine, 2, 201-211 (2007).
  35. Hansen JC, Lim JY, Siedlecki CA, Donahue HJ. "Effect of Surface Nanoscale Topography on Elastic Modulus of Individual Osteoblastic Cells as Determined by Atomic Force Microscopy". Journal of Biomechanics 40: 2865-2871 (2007).
  36. Zhuo R, Siedlecki CA, Vogler EA. "Competitive-Protein Adsorption in Contact Activation of Blood Factor XII". Biomaterials 28: 4355-4369 (2007).

Parts of Books:

  1. Gay CV, Donahue HJ, Siedlecki CA, Vogler EA. "Cell Biology of the Skeletal System: Osteoblasts, Osteocytes Osteoclasts, Bone Marrow Stromal Cells", in Bone Tissue Engineering, Hollinger JO, Einhorn TA, Doll B, Sfeir C. CRC Press, Boca Raton FL (2005).