Core Research Facilities

Research Resources/Core Facilities News and Events

  • Our new Leica EM UC7 ultramicrotome was installed April 26, 2016 in the TEM facility (C1727). This new ultramicrotome offers a range of outstanding features and benefits for TEM sample preparation, optimizing preparation of semi- and ultrathin sections. It also can prepare perfect, smooth surfaces from biological and industrial samples for subsequent TEM, SEM, AFM and LM Imaging. For details, contact Dr. Han Chen at

  • The Zebrafish Functional Genomics Core held a Grand Opening Event from 1:45 to 5 p.m. April 13, 2016 in the Junker Auditorium. The event featured a keynote talk by David Grunwald, Ph.D., Professor of Human Genetics, Department of Human Genetics, University of Utah, talks by several Penn State faculty members, and a tour of the facilities. See a photo slideshow from the event here.

  • We are pleased to announce that Dr. Han Chen started as Director of our Transmission Electron Microscopy facility Feb. 29, where he will continue the long tradition of providing excellent sample preparation, image acquisition, and instrument maintenance services. After receiving his MD and PhD in China, Dr. Chen alternated between being a post-doctoral scholar at the University of Nebraska - Lincoln and holding faculty positions at Sun Yat-sen University in China. Most recently, Dr. Chen has spent the past 10 years as a Research Scientist in the Microscopy Core Facility at the Biotechnology Center at the University of Nebraska Lincoln, where he specialized in Electron Microscopy. An author of 55 publications, Dr. Chen brings both a strong research background and extensive expertise in Electron Microscopy to share with our researchers here at the College of Medicine and beyond.

  • Leica Microsystems brought its Stimulated Emission Depletion (STED) Super-Resolution microscope demo unit to Penn State College of Medicine November 9-17, 2015. STED is a Nobel Prize winning technique, which overcomes diffraction limits in light microscopy (down to ~50-nm lateral/130-nm axial compared to 200-nm lateral/500-nm axial in Confocal microscopes) This level of resolving power is approaching that of electron microscopes and since the super-resolution microscopes are fluorescence based, STED modality is able to generate nanoscale multiple intra-cellular color images simultaneously.

    For details and to evaluate the capabilities of STED as it applies to your specific areas of research, please visit the following website: Geoff Daniel of Leica is happy to discuss STED with you. His contact information is or (610) 721-7133.

  • Congratulations and best wishes for retirement to Roland Myers after 36 years of exemplary Electron Microscopy sample prep and images! His retirement party was held in late October.

  • The Penn State Hershey Pulmonary Immunology and Physiology (PIP) Core is now open for business.  The Core's purpose is to aid investigators in the development and testing of small animal models to be used for pre-clinical pulmonary research.  It is a BSL2 facility that allows the assessment of pulmonary function related to many clinical situations.  It offers services including oxygen profiling, infection and treatment, and the ability to deliver, measure, and test the pre-clinical potential of therapeutic interventions via aerosol, as well as housing of the small animals used in these studies. The PIP Core is located in the Department of Comparative Medicine (Room CG737) and is operated under the oversight of the Department of Pediatrics.  To learn more about the PIP Core or to schedule an appointment go to
  • April 2015 - Dr Thomas Abraham's Shared Instrumentation Grant for a new Nikon A1 MP+ Multiphototon Microscope System was awarded.   This advanced imaging instrument has deep tissue imaging and fast hybrid scanning capabilities.  Congratulations to Dr. Abraham and the Imaging Core Facility!
  • Thanks to the Capital Equipment Purchase Program made available by the Office of the Vice Dean for Research & Graduate Studies, the following new equipment is now available to researchers:

QuantStudio Real-Time PCR System & Digital PCR Reader are located in the Genome Sciences Core (C2705) Contact Rob Brucklacher for information
14 color LSR Fortessa located in the Flow Cytometry Core (C3603) Contact Nate Sheaffer for information
Seahorse XF96 Extracellular Flux Analyzer is located in C2705. Contact Wade Edris wedris@hmc.psu.ed for information.

  • The Genomics Core Facility sponsored LifeTech seminars on Digital PCR and RNA SEQ -  these were recorded by Mediasite broadcast, and can be viewed from your desktop when available.
  • May 2012 - Dr. Colin Barnstable's Shared Instrumentation Grant for a new Live-Cell Confocal Microscope was funded. Congratulations Dr. Barnstable and group!
  • April 2012 - Dr. Susan Hafenstein's Shared Instrumentation Grant for a new CryoEM Microscope was funded, and institutional funds were added to purchase the new system. Congratulations Dr. Hafenstein and group!

About The Labs


Citation for Publications

All research tools and work contributed by our Core Facilities should minimally be acknowledged in any publications. Guidelines for authorship have been established by the International Committee of Medical Journal Editors and similar organizations, and significant intellectual contribution is the ONLY important criterion, not whether a service is paid for or free.

>> Read more and get the specific language to use for proper citation/acknowledgement of Core Facilities Use