Publications from the Lab


Some recent publications which used data generated in the Mass Spectrometry Core are listed below.  Mass Spec Facility staff authors are in bold:

Mandal A, Mandal S, Park MH. Global quantitative proteomics reveal up-regulation of endoplasmic reticulum stress response proteins upon depletion of eIF5A in HeLa cells. Sci Rep. 2016 May 16;6:25795. doi: 10.1038/srep25795. PMID: 27180817

Lu D, Ni W, Stanley BA, Ma H. Proteomics and transcriptomics analyses of Arabidopsis floral buds uncover important functions of ARABIDOPSIS SKP1-LIKE1. BMC Plant Biol. 2016 Mar 3;16(1):61. doi: 10.1186/s12870-015-0571-9. PMID: 26940208

Stanley BA, Deering T, Fox TE (2015) "Sphingoproteomics: Proteomic Strategies to Examine Sphingolipid Biology" pp. 359-384 in Bioactive Sphingolipids in Cancer Biology and Therapy eds Yusuf A. Hannun, Chiara Luberto, Cungui Mao and Lina Marie Obeid. Springer International Publishing, Switzerland 2015 DOI 10.1007/978-3-319-20750-6

Miklossy G, Youn UJ, Yue P, Zhang M, Chen CH, Hilliard TS, Paladino D, Li Y, Choi J, Sarkaria JN, Kawakami JK, Wongwiwatthananukit S, Chen Y, Sun D, Chang LC, Turkson J. (2015) "Hirsutinolide Series Inhibit Stat3 Activity, Alter GCN1, MAP1B, Hsp105, G6PD, Vimentin, TrxR1, and Importin a-2 Expression, and Induce Antitumor Effects against Human Glioma." J Med Chem. 2015 Sep 17. [Epub ahead of print] PMID: 26331426

Shukla, S; Shankavaram, UT; Nguyen, P; Stanley, BA; Smart, DK (2015) "Radiation-induced alteration of the brain proteome: understanding the role of the Sirtuin 2 deacetylase in a murine model" J. Proteome Res., Article ASAP DOI: 10.1021/acs.jproteome.5b00083 Publication Date (Web): September 16, 2015. PMID: 26373435

Morad SA, Tan SF, Feith DJ, Kester M, Claxton DF, Loughran TP Jr, Barth BM, Fox TE, Cabot MC (2015) "Modification of sphingolipid metabolism by tamoxifen and N-desmethyltamoxifen in acute myelogenous leukemia--Impact on enzyme activity and response to cytotoxics." Biochim Biophys Acta. 2015 Jul;1851(7):919-28. doi: 10.1016/j.bbalip.2015.03.001. PMID:25769964

Rice SJ, Liu X, Miller B, Joshi M, Zhu J, Caruso C, Gilbert C, Toth J, Reed M, Rassaei N, Das A, Barochia A, El-Bayoumy K, Belani CP. (2015) Proteomic profiling of human plasma identifies apolipoprotein E as being associated with smoking and a marker for squamous metaplasia of the lung. Proteomics. 2015 Sep;15(18):3267-77. doi: 10.1002/pmic.201500029. Epub 2015 Jul 3. PMID: 26058877

Dick TE, Hengst JA, Fox TE, Colledge AL, Kale VP, Sung SS, Sharma A, Amin S, Loughran TP Jr, Kester M, Wang HG, Yun JK (2015) "The apoptotic mechanism of action of the sphingosine kinase 1 selective inhibitor SKI-178 in human acute myeloid leukemia cell lines." J Pharmacol Exp Ther. 2015 Mar;352(3):494-508. doi: 10.1124/jpet.114.219659 PMID:25563902

Das A, Bortner JD Jr., Aliaga C, Cooper T, Stanley A, Stanley BABelani CP, El-Bayoumy K (2015) "Proteomic profiling of hyperplasia/atypia and adenoma-induced by NNK in mouse lung identified multiple proteins as potential biomarkers for early detection." EuPA Open Proteomics 9: 23-33.  

Wase N, Black P, Stanley B, DiRusso C. (2014) Integrated Quantitative Analysis of Nitrogen Stress Response in Chlamydomonas Reinhardtii Using Metabolite and Protein Profiling. J. Proteome Res., 13(3):1373-1396 DOI: 10.1021/pr400952z. PMID: 24528286 

Giardina BJ, Stanley BA, Chiang HL. (2014) Glucose induces rapid changes in the secretome of Saccharomyces cerevisiae. Proteome Sci. 12(1):9. doi: 10.1186/1477-5956-12-9. PMID: 24520859

Olsen KC, Xu Y, Chen G, Hajnal, A, Lynch CJ. (2014) Alloisoleucine differentiates the branched-chain aminoacidemia of obese Zucker and diet-induced obesity (DIO) rats. Nature Obesity 22(5):1212-5. doi:10.1002/oby.20691 PMID: 24415721

Dai, JP, Tabakovich, T, Loc, W, Butler, A, McGovern CO, Adair, JH, Butler, PJ, Stanley, BA, Smith, JP, Matters, GL, and Kester, M. (2013)  Development of an Ultrasensitive LC–MS-MS Method for Determination of 5-Fluorouracil in Mouse Plasma. Current Trends in Mass Spectrometry October 2013, pp. 2-9.

Chung SH, Rosa C, Scully ED, Peiffer M, Tooker JF, Hoover K, Luthe DS, Felton GW. (2013) Herbivore exploits orally secreted bacteria to suppress plant defenses. Proc Natl Acad Sci U S A. 110(39):15728-33. PMID: 24019469

Bansal R, Helmus RA, Stanley BA, Zhu J, Liermann LJ, Brantley SL, Tien M (2013) Survival During Long Term Starvation: Global Proteomics Analysis of Geobacter sulfurreducens under Prolonged Electron Acceptor Limitation. J. Proteome Res.,  • DOI: 10.1021/pr400266m • Publication Date (Web): 27 Aug 2013

Skibinski C.G., Thompson, H.J. Das, A. Manni, A., Bortner, Stanley, A., Stanley, B., El-Bayoumy, K. (2013) Proteomic Changes Induced by Effective Chemopreventive Ratios of n-3:n-6 Fatty Acids and Tamoxifen against MNU-Induced Mammary Cancer in the Rat. Cancer Prevention Research. published 23 July 2013, 10.1158/1940-6207.CAPR-13-0152

Patton SM, Cho YW, Clardy TW, Allen RP, Earley CJ, Connor JR. (2013) Proteomic analysis of the cerebrospinal fluid of patients with restless legs syndrome/Willis-Ekbom disease. Fluids Barriers CNS. 2013 Jun 7;10(1):20. doi: 10.1186/2045-8118-10-20.

Jones KA, Kim PD, Patel BB, Kelsen SG, Braverman A, Swinton DJ, Gafken PR, Jones LA, Lane WS, Neveu JM, Leung HC, Shaffer SA, Leszyk JD, Stanley BA, Fox TE, Stanley A, Hall MJ, Hampel H, South CD, de la Chapelle A, Burt RW, Jones DA, Kopelovich L, Yeung AT. (2013). Immunodepletion plasma proteomics by tripleTOF 5600 and Orbitrap elite/LTQ-Orbitrap Velos/Q exactive mass spectrometers. J Proteome Res. 2013 Oct 4;12(10):4351-65. doi: 10.1021/pr400307u. PMID: 24004147

Jones K, Kim K, Patel B, Kelsen S, Braverman A, Swinton D, Gafken P, Jones L, Lane W, Neveu J, Leung H, Shaffer S, Leszyk J, Stanley B, Fox T, Stanley A, and Yeung, A (2013). Mass Spectrometry Data Collection in Parallel at Multiple Core Facilities Operating TripleTOF 5600 and Orbitrap Elite/Velos Pro/Q Exactive Mass Spectrometers. J Biomol Tech. 2013 May; 24(Suppl): S52. PMCID: PMC3635246

Olsen KC, Chen G, Lynch CJ. (2013) Quantification of Branched-Chain Ketoacids in Tissue by Ultra Fast Liquid Chromatography-Mass Spectrometry  Analytical Biochemistry (2013) Aug 15;439(2):116-22. doi: 10.1016/j.ab.2013.05.002. Epub 2013 May 14. PMID: 23684523

Dennis MD, Shenberger JS, Stanley BA, Kimball SR, Jefferson LS.(2013) Hyperglycemia Mediates a Shift from Cap-Dependent to Cap-Independent Translation via a 4E-BP1 Dependent Mechanism. Diabetes. 2013 Feb 22. [Epub ahead of print] PMID: 23434932

Barth BM, Shanmugavelandy SS, Kaiser JM, McGovern C, Altinoglu EI, Haakenson JK, Hengst JA, Gilius EL, Knupp SA, Fox TE, Smith JP, Ritty TM, Adair JH, Kester M. (2013)  PhotoImmunoNanoTherapy Reveals an Anticancer Role for Sphingosine Kinase 2 and Dihydrosphingosine-1-Phosphate.  ACS Nano. 2013 Feb 14. [Epub ahead of print]

Das A., Bortner Jr. JD, Aliaga CA, Baker A, Stanley A, Stanley BA, Kaag M, Richie Jr. JP, El-Bayoumy K. (2013) Changes in Proteomic Profiles in Different Prostate Lobes of Male Rats throughout Growth and Development and Aging Stages of the Life Span. The Prostate 73(4):363-75. PMID: 22911278

Kaiser JM, Imai H, Haakenson JK, Brucklacher RM, Fox TE, Shanmugavelandy SS, Unrath KA, Pedersen MM, Dai P, Freeman WM, Bronson SK, Gardner TW, Kester M. (2013)  Nanoliposomal minocycline for ocular drug delivery.  Nanomedicine. 2013 Jan;9(1):130-40. doi: 10.1016/j.nano.2012.03.004. Epub 2012 Mar 28.

Watters RJ, Fox TE, Tan SF, Shanmugavelandy S, Choby JE, Broeg K, Liao J, Kester M, Cabot MC, Loughran TP, Liu X. (2013)  Targeting glucosylceramide synthase synergizes with C(6)-ceramide nanoliposomes to induce apoptosis in natural killer cell leukemia.   Leuk Lymphoma. 2013 Jun;54(6):1288-96. (2012 Dec 31. [Epub ahead of print])

Fox TE, Young MM, Pedersen MM, Han X, Gardner TW, Kester M. (2012) Diabetes diminishes phosphatidic acid in the retina: a putative mediator for reduced mTOR signaling and increased neuronal cell death.   Invest Ophthalmol Vis Sci. 2012 Oct 19;53(11):7257-67. doi: 10.1167/iovs.11-7626.

Madhunapantula SV, Hengst J, Gowda R, Fox TE, Yun JK, Robertson GP. (2012) Targeting sphingosine kinase-1 to inhibit melanoma.  Pigment Cell Melanoma Res. 2012 Mar;25(2):259-74. doi: 10.1111/j.1755-148X.2012.00970.x.  

Lancaster, T.L., Jefferson, S.J., Hunter, J.C., Lopez, V.U., Van Eyk, J., Lakatta, E.G. and Korzick, D.H. (2012) Quantitative Proteomic Analysis Reveals Novel Mitochondrial Targets of Estrogen Deficiency in the Aged Female Rat Heart. Physiol Genomics 44(20): 957-969. PMID: 22930739

Moon, MS, McDevitt, E, Stanley, BA, Krzeminski, J, Amin, S, Aliaga, C, Miller, T, Isom, H. (2012) Elevated Hepatic Iron Activates NF-E2-Related Factor 2 (NRF2) Regulated Pathway in a Dietary Iron Overload Mouse Model Toxicol. Sci. 129(1): p. 74-85. PMID: 22649188

Liu, X, Liu, D, Qian, D, Dai, J, An, Y, Jiang, S, Stanley, BA, Yang, J, Wang, B, Liu, X, Liu, DX. (2012). Nucleophosmin (NPM1/B23) Interacts with Activating Transcription Factor 5 (ATF5) Protein and Promotes Proteasome- and Caspase-dependent ATF5 Degradation in Hepatocellular Carcinoma Cells. J Biol Chem 287(23):19599-609. PMID: 22528486

Giardina, BJ, Stanley, BA, Chiang, H-L. (2012) Comparative Proteomic Analysis of Transition of Saccharomyces cerevisiae from Glucose-Deficient Medium to Glucose-Rich Medium. Proteome Science 10(1): 40. PMID: 22691627

Kuhns EH, Seidl-Adams I, Tumlinson J.H. (2012) A lepidopteran aminoacylase (L-ACY-1) in Heliothis virescens (Lepidoptera:Noctuidae) gut lumen hydrolyzes fatty acid-amino acid conjugates, elicitors of plant defense Insect Biology & Molecular Biology 42(1): 32-40

Ludgate L, Adams C, Hu J. (2011) "Phosphorylation state-dependent interactions of hepadnavirus core protein with host factors." PLoS One. 2011;6(12):e29566. doi: 10.1371/journal.pone.0029566. Epub 2011 Dec 22. PMID: 22216318.

Fox, TE, Bewley, MC, Unrath, KA, Pedersen, MM, Anderson, RA, Jung, DY, Jefferson, LS, Kim, JK, Bronson, SK, Flanagan, JM, Kester, M. (2011). Circulating sphingolipid biomarkers in models of type 1 diabetes J Lipid Res. 2011 March; 52(3): 509–517. PMCID: PMC3035687

Hankins JL, Fox TE, Barth BM, Unrath KA, Kester M. (2011) Exogenous ceramide-1-phosphate reduces lipopolysaccharide (LPS)-mediated cytokine expression.  J Biol Chem. 2011 Dec 30;286(52):44357-66. doi: 10.1074/jbc.M111.264010. Epub 2011 Nov 7.

Jiang Y, DiVittore NA, Kaiser JM, Shanmugavelandy SS, Fritz JL, Heakal Y, Tagaram HR, Cheng H, Cabot MC, Staveley-O'Carroll KF, Tran MA, Fox TE, Barth BM, Kester M. (2011) Combinatorial therapies improve the therapeutic efficacy of nanoliposomal ceramide for pancreatic cancer.  Cancer Biol Ther. 2011 Oct 1;12(7):574-85. Epub 2011 Oct 1.

O'Neill SM, Yun JK, Fox TE, Kester M. (2011)  Transcriptional regulation of the human neutral ceramidase gene.  Arch Biochem Biophys. 2011 Jul;511(1-2):21-30. doi: 10.1016/ Epub 2011 Apr 22.

Lancaster TS, Jefferson SJ, Korzick DH (2011)  Local delivery of a PKC-epsilon-activating peptide limits ischemia reperfusion injury in the aged female rat heart. Am J Physiol Regulatory Integrative Comp Physiol. 301(5): R1242-R1249

Wilson RT, Roff A, Dai P, Fortugno T, Douds J, Chen G, Grove GL, Nikiforova SO, Barnholtz-Sloan J, Frudakis T, Chinchilli V, Hartmann T, Demers L, Shriver MD, Canfield V, Cheng K (2011)  Genetic ancestry, skin reflectance and pigmentation genotypes in association with serum vitamin D metabolite balance.  Horm Mol Biol Clin Invest 7(1):279-293 DOI 10.1515/HMBCI.2011.021

Losiewicz MK, Fort, PE. (2011) Diabetes impairs the neuroprotective properties of retinal alpha-crystallins. Invest. Ophthalmol. Vis. Sci. published 5 April 10.1167/iovs.10-6931

Fogle RL, Hollenbeak CS, Stanley BA, Vary TC, Kimball SR, Lynch CJ. (2011) Functional proteomic analysis reveals sex-dependent differences in structural and energy-producing myocardial proteins in rat model of alcoholic cardiomyopathy. Physiol Genomics 43(7): p. 346-356 PMID: 21245415

Bortner JD, Richie JP, Das A, Liao J, Umstead TM, Stanley A, Stanley BA, Belani CP, El-Bayoumy K. (2011) Proteomic Profiling of Human Plasma by iTRAQ Reveals Down-Regulation of ITI-HC3 and VDBP by Cigarette Smoking. J Proteome Res; Mar 4;10(3):1151-9. PMID: 21186835

VanGuilder HD, Bixler GV, Kutzler L, Brucklacher RM, Bronson SK, Kimball SR, Freeman WM. (2011) Multi-modal proteomic analysis of retinal protein expression alterations in a rat model of diabetic retinopathy. PLoS One. Jan 13;6(1):e16271

Desai, D., Salli, U., Vrana, K. E and Amin, S. (2010). SelSA, selenium analogs of SAHA as potent histone deacetylase inhibitors. Biorganic and Med Chem Letters 20, 2044-2047. PMID: 20167479

Desai, D., Madhunapantula, S.V., Gowdahalli, K., Sharma, A., Chandagaludoreswany, R., El-Bayoumy, K., Robertson, G.P. and Amin, S. (2010). Synthesis and characterization of a novel iNOS/Akt inhibitor Se,Se'-1,4-phenylenebis(1,2-ethanediyl)bisisoselenourea (PBISe)-against colon cancer. Biorganic and Med Chem Letters 20, 2038-2043. PMID: 20153642

Fogle RL, Lynch CJ, Palopoli M, Deiter G, Stanley BA, Vary TC. (2010) Impact of Chronic Alcohol Ingestion on Cardiac Muscle Protein Expression. Alcohol Clin Exp Res. (2010) Jul;34(7):1226-34 PMID: 20477769

Moura, AA, Souza CE, Stanley BA, Chapman DA, Killian GJ.  (2010) Proteomics of cauda epididymal fluid from mature Holstein bulls. J Proteomics. Sep 10;73(10):2006-20 PMID: 20601273

Ali M, Umstead TM, Haque R, Mikerov AN, Freeman WM, Floros J, Phelps DS. (2010) Differences in the BAL proteome after Klebsiella pneumoniae infection in wild type and SP-A-/- mice. Proteome Sci. 2010 Jun 17;8:34. PMID: 20565803

Umstead TM, Lu CJ, Freeman WM, Myers JL, Clark JB, Thomas NJ, Chinchilli VM, Vrana KE, Undar A, Phelps DS. (2010) Dual-platform proteomics study of plasma biomarkers in pediatric patients undergoing cardiopulmonary bypass. Pediatr Res. 2010 Jun;67(6):641-9. PMID: 20308938

Khanna MR, Stanley BA, Thomas GH. (2010) Towards a membrane proteome in Drosophila: a method for the isolation of plasma membrane. BMC Genomics. 2010 May 12;11(1):302. PMID: 20462449.

Winter JN, Fox TE, Kester M, Jefferson LS, Kimball SR (2010) Phosphatidic acid mediates activation of mTORC1 through the ERK signaling pathway Am J Physiol Cell Physiol 299:C335-C344, 2010 First published April 2010; doi:10.1152/ajpcell.00039.2010

VanGuilder HD, Yan H, Farley JA, Sonntag WE, Freeman WM. (2010) Aging alters the expression of neurotransmission-regulating proteins in the hippocampal synaptoproteome. J Neurochem. 2010 Jun;113(6):1577-88. Epub 2010 Mar 31 PMID: 20374424

Zhao Z, Stanley BA, Zhang W, Assmann SM (2010) ABA-regulated G protein signaling in Arabidopsis guard cells: a proteomic perspective. J Proteome Res. 2010 5;9(4):1637-47. PMID: 20166762

Barthéléry, M., Jaishankar, A., Salli, U., and Vrana, K. E. (2009). Reptin52 expression during in vitro neural differentiation of human embryonic stem cells. Neurosci Lett 452, 47-51. PMID: 19444951

Barthéléry M, Salli U, Freeman WM, Vrana KE. (2009) 2-DIGE identification of differentially expressed hNRNPs and transcription factors during neural differentiation of human ES cells. Proteomics: Clinical Applications 3:505-514, 2009

Bortner JD Jr, Das A, Umstead TM, Freeman WM, Somiari R, Aliaga C, Phelps DS, El-Bayoumy K. (2009) Down-regulation of 14-3-3 isoforms and annexin A5 proteins in lung adenocarcinoma induced by the tobacco-specific nitrosamine NNK in the A/J mouse revealed by proteomic analysis. J Proteome Res. 2009 Aug;8(8):4050-61. PMID: 19563208

Boyiri, T., Somiari, R. I., Russell, S., Aliaga, C., and El-Bayoumy, K. (2009). Proteomics of rat prostate lobes treated with 2-N-hydroxylamino-1-methyl-6-phenylimidazo[4,5-b]pyridine, 5alpha-dihydrotestosterone, individually and in combination. Int J Oncol 35, 559-567. PMID: 19639176

Crown PL, Hurst WJ. (2009) Evidence of cacao use in the Prehispanic American Southwest. Proc Natl Acad Sci U S A. 2009 Feb 2. 106(7): 2110-2113 PMID: 19188605

Culnan DM, Cooney RN, Stanley B, Lynch CJ. (2009) Apolipoprotein A-IV, a Putative Satiety/Antiatherogenic Factor, Rises After Gastric Bypass. Obesity (Silver Spring). 2009 Jan;17(1):46-52. PMID: 18948973

Wijesinghe DS, Allegood JC, Gentile LB, Fox TE, Kester M, Chalfant CE. (2009) Use of high performance liquid chromatography-electrospray ionization-tandem mass spectrometry for the analysis of ceramide-1-phosphate levels.  J Lipid Res. 2010 Mar;51(3):641-51. doi: 10.1194/jlr.D000430. Epub 2009 Aug 4.

Das, A., Bortner, J., Desai, D., Amin, S., and El-Bayoumy, K. (2009). The selenium analog of the chemopreventive compound S,S'-(1,4-phenylenebis[1,2-ethanediyl])bisisothiourea is a remarkable inducer of apoptosis and inhibitor of cell growth in human non-small cell lung cancer. Chem Biol Interact 180, 158-164. PMID: 19497413

Feng B, Li L, Zhou X, Stanley B, Ma H. (2009) Analysis of the Arabidopsis Floral Proteome: Detection of over 2,000 Proteins and Evidence for Posttranslational Modifications. J Integr Plant Biol. 2009 Feb;51(2):207-23. PMID: 19200160

Freeman WM, VanGuilder HD, Bennett C, Sonntag WE. (2009) Cognitive performance and age related changes in the hippocampal proteome. Neuroscience 159:183-9, 2009. PMID: 

Haque R, Umstead TM, Freeman WM, Floros J, Phelps DS. (2009) The impact of surfactant protein-A on ozone-induced changes in the mouse broncoalveolar lavage proteome. Proteome Sci. 7:12, 2009

Hengst JA, Guilford JM, Fox TE, Wang X, Conroy EJ, Yun JK. (2009) Sphingosine kinase 1 localized to the plasma membrane lipid raft microdomain overcomes serum deprivation induced growth inhibition. Arch Biochem Biophys. 492(1-2):62-73, 2009. PMID: 19782042.

Hurst WJ, Stanley B, Glinski JA, Davey M, Payne MJ and Stuart DA (2009) Characterization of Primary Standards for Use in the HPLC Analysis of the Procyanidin Content of Cocoa and Chocolate Containing Products. Molecules 14(10): 4136-4146, 2009 doi:10.3390/molecules14104136

Jaishankar A, Barthéléry M, Freeman WM, Salli U, Vrana KE. (2009) Human Embryonic and Mesenchymal Stem Cells Express Different Nuclear Proteomes. Stem Cells Develop. 18:793-802, 2009

Lee, J. I., Nian, H., Cooper, A. J., Sinha, R., Dai, J., Bisson, W. H., Dashwood, R. H., and Pinto, J. T. (2009). Alpha-keto acid metabolites of naturally occurring organoselenium compounds as inhibitors of histone deacetylase in human prostate cancer cells. Cancer Prev Res (Phila Pa) 2, 683-693. PMID: 19584079

Lull ME, Erwin MS, Patel KM, Morgan D, Roberts DCS, Vrana KE, Freeman WM. (2009) Persistent proteomic alterations in medial prefrontal cortex with abstinence from cocaine self-administration. Proteomics: Clinical Applications 3:462-472, 2009. 

Nowak, M. G., Sudol, M., Lee, N. E., Konsavage, W. M., Jr., and Katzman, M. (2009). Identifying amino acid residues that contribute to the cellular-DNA binding site on retroviral integrase. Virology 389, 141-148. PMID: 19447461

Nyland, S. B., and Loughran, T. P. (2009). Putting HIV-1 apoptosis mediators to work against cancer: A killer job, with benefits. Cancer Biol Ther 8, 188-191. PMID: 19182513

Popova, E. Y., Krauss, S. W., Short, S. A., Lee, G., Villalobos, J., Etzell, J., Koury, M. J., Ney, P. A., Chasis, J. A., and Grigoryev, S. A. (2009). Chromatin condensation in terminally differentiating mouse erythroblasts does not involve special architectural proteins but depends on histone deacetylation. Chromosome Res 17, 47-64. PMID: 19172406

Purdy, JG, Flanagan JM, I. J. Ropson IJ, and Craven, R. C. (2009) Retroviral capsid assembly: a role for the CA dimer in initiation. J. Mol. Biol. 389(2):438-51, 2009. PMID: 19361521

Sharma, A., Sharma, A. K., Madhunapantula, S. V., Desai, D., Huh, S. J., Mosca, P., Amin, S., and Robertson, G. P. (2009). Targeting Akt3 Signaling in Malignant Melanoma Using Isoselenocyanates. Clin Cancer Res 15, 1674-1685. PMID: 19208796

Sundstrom JM, Tash BR, Murakami T, Flanagan JM, Bewley MC, Stanley BA, Gonsar KB, Antonetti DA (2009) Identification and Analysis of Occludin Phosphosites: A Combined Mass Spectrometry and Bioinformatics Approach. J Proteome Res. 8(2):808-817 PMID: 19125584

Sundstrom JM, Sundstrom CJ, Sundstrom SA, Fort PE, Rauscher RL, Gardner TW, Antonetti DA. (2009) Phosphorylation Site Mapping of Endogenous Proteins: A Combined MS and Bioinformatics Approach. J Proteome Res. Feb 6;8(2):798-807. PMID: 19125583

Umstead TM, Freeman WM, Phelps DS.  (2009) Age-related changes in the expression and oxidation of bronchoalveolar lavage proteins in the rat. AJP: Lung Cellular and Molecular Physiology 296:L14-29, 2009

Zou B, Yan H, Kawasaki F, Ordway RW. (2008) MAP1 structural organization in Drosophila: in vivo analysis of FUTSCH reveals heavy- and light-chain subunits generated by proteolytic processing at a conserved cleavage site. Biochem J. 2008 Aug 15;414(1):63-71. doi: 10.1042/BJ20071449. PMID: 18419581

Zhao Z, Zhang W, Stanley BA, Assmann SM. (2008) Functional Proteomics of Arabidopsis thaliana Guard Cells Uncovers New Stomatal Signaling Pathways. Plant Cell. 2008 Dec;20(12):3210-26. PMID: 19114538

O'Neill SM, Olympia DK, Fox TE, Brown JT, Stover TC, Houck KL, Wilson R, Waybill P, Kozak M, Levison SW, Weber N, Karavodin LM, Kester M. (2008) C(6)-Ceramide-Coated Catheters Promote Re-Endothelialization of Stretch-Injured Arteries.  Vasc Dis Prev. 2008 Aug 1;5(3):200-210.

Geguchadze RN, Coe C, Lubach GR, Clardy TW, Beard JL, Connor JR. (2008) CSF Proteomic Analysis Reveals Persistent Iron Deficiency-induced Alterations In Non-human Primate Infants  J Neurochem. 2008 Apr;105(1):127-36.

Barthéléry, M., Salli, U., and Vrana, K. E. (2008). Enhanced nuclear proteomics. Proteomics 8, 1832-1838. PMID: 18384104

Chen KM, Spratt TE, Stanley BA, De Cotiis DA, Bewley MC, Flanagan JM, Desai D, Das A, Fiala ES, Amin S, El-Bayoumy K. (2007) Inhibition of nuclear factor-kappaB DNA binding by organoselenocyanates through covalent modification of the p50 subunit. Cancer Res. 67(21):10475-83. PMID: 17974991

Chang SI, El-Bayoumy K, Sinha I, Trushin N, Stanley BA, Pittman B, Prokopczyk B. (2007) 4-(Methylnitrosamino)-I-(3-Pyridyl)-1-Butanone Enhances the Expression of Apolipoprotein A-I and Clara Cell 17-kDa Protein in the Lung Proteomes of Rats Fed a Corn Oil Diet but not a Fish Oil Diet. Cancer Epidemiol Biomarkers Prev 16(2): 228-35. PMID: 17301254

Fort PE, Freeman WM, Losiewicz MK, Singh RS, Gardner TW. (2009) The retinal proteome in experimental diabetic retinopathy: Up-regulation of crystallins and reversal by systemic and periocular insulin. Mol Cell Proteomics. Apr;8(4):767-79 . PMID: 19049959

Ritty, TM, Frauenhoffer, E, Fox, EJ, Stanley, BA (2008) "Tumor typing by proteomic analysis of formalin fixed sample ECM" Matrix Biology 27:32-32, 2008. DOI: 10.1016/j.matbio.2008.09.309

Kester, M., Heakal, Y., Fox, T., Sharma, A., Robertson, G. P., Morgan, T. T., Altinoglu, E. I., Tabakovic, A., Parette, M. R., Rouse, S. M., et al. (2008). Calcium phosphate nanocomposite particles for in vitro imaging and encapsulated chemotherapeutic drug delivery to cancer cells. Nano Lett 8, 4116-4121. PMID: 19367878

Konsavage, W. M., Jr., Sudol, M., and Katzman, M. (2008). Effects of varying the spacing within the D,D-35-E motif in the catalytic region of retroviral integrase. Virology 379, 223-233. PMID: 18687451

Lin, L., and Hu, J. (2008). Inhibition of hepadnavirus reverse transcriptase-epsilon RNA interaction by porphyrin compounds. J Virol 82, 2305-2312. PMID: 18094191

Lin, L., Wan, F., and Hu, J. (2008). Functional and Structural dynamics of Hepadnavirus Reverse Transcriptase During Protein-Primed Initiation of Reverse Transcription: Effects of Metal Ions. J Virol. 82, 5703-14. PMID: 18400846

Madhunapantula, S. V., Desai, D., Sharma, A., Huh, S. J., Amin, S., and Robertson, G. P. (2008). PBISe, a novel selenium-containing drug for the treatment of malignant melanoma. Mol Cancer Ther 7, 1297-1308. PMID: 18483317

Purdy JG, Flanagan JM, Ropson IJ, Rennoll-Bankert KE, Craven RC. (2008) Critical role of conserved hydrophobic residues within the major homology region in mature retroviral capsid assembly. J Virol. 2008 Jun;82(12):5951-61. PMID: 18400856

Lull ME, Carkaci-Salli N, Freeman WM, Myers JL, Midgley FM, Thomas NJ, Kimatian SJ, Vrana KE, Ündar A. (2008) Plasma proteomic biomarkers in pediatric cardiac patients undergoing cardiopulmonary bypass procedures. J. Pediatric Res. 2008; 63:638-644. PMID: 18317239

Salli, U., Fox, T. E., Carkaci-Salli, N., Sharma, A., Robertson, G. P., Kester, M., and Vrana, K. (2008). Propagation of undifferentiated human embryonic stem cells with nano-liposomal ceramide. Stem Cells Dev 18, 55-65. PMID: 18393629

Sharma, A. K., Sharma, A., Desai, D., Madhunapantula, S. V., Huh, S. J., Robertson, G. P., and Amin, S. (2008). Synthesis and anticancer activity comparison of phenylalkyl isoselenocyanates with corresponding naturally occurring and synthetic isothiocyanates. J Med Chem 51, 7820-7826. PMID: 19053750

Stover, T. C., Kim, Y. S., Lowe, T. L., and Kester, M. (2008). Thermoresponsive and biodegradable linear-dendritic nanoparticles for targeted and sustained release of a pro-apoptotic drug. Biomaterials 29, 359-369. PMID: 17964645

Zolnik, B. S., Stern, S. T., Kaiser, J. M., Heakal, Y., Clogston, J. D., Kester, M., and McNeil, S. E. (2008). Rapid Distribution of Liposomal Short-Chain Ceramide In Vitro and In Vivo. Drug Metab Dispos 36, 1709-1715. PMID: 18490436

Consultations, recommendations for reagents and procedures, and instructions are all freely available, please contact Dr. Bruce Stanley by email at, or by telephone at (717) 531-5329.