About The Labs
- Overview of Core Labs and downloadable Facility Details available here
- Dr. Bruce A. Stanley - Director, Section of Research Resources
- Core Labs News
All research tools and work contributed by our Core Facilities should minimally be acknowledged in any publications. Guidelines for authorship have been established by the International Committee of Medical Journal Editors and similar organizations, and significant intellectual contribution is the ONLY important criterion, not whether a service is paid for or free.
Research Resources/Core Facilities News and Events
Leica Microsystems will have their Stimulated Emission Depletion (STED) Super-Resolution microscope demo unit here at Penn State College of Medicine November 9-17, 2015. STED is a Nobel Prize winning technique, which overcomes diffraction limits in light microscopy (down to ~50-nm lateral/130-nm axial compared to 200-nm lateral/500-nm axial in Confocal microscopes) This level of resolving power is approaching that of electron microscopes and since the super-resolution microscopes are fluorescence based, STED modality is able to generate nanoscale multiple intra-cellular color images simultaneously.
The location for the demonstration will be in room C4740C. To sign up to participate in the demo and evaluate the capabilities of STED as it applies to your specific areas of research, please visit the following website: http://www.leica-microsystems.com/penn-state-sted/. You can also download the sample prep details from the above website.
Geoff Daniel of Leica is happy to discuss the STED sample prep details with you. His contact information is email@example.com or call (610) 721-7133.
Congratulations and best wishes for retirement to Roland Myers after 36 years of exemplary Electron Microscopy sample prep and images! His retirement party was held in late October.
- The Penn State Hershey Pulmonary Immunology and Physiology (PIP) Core is now open for business. The Core's purpose is to aid investigators in the development and testing of small animal models to be used for pre-clinical pulmonary research. It is a BSL2 facility that allows the assessment of pulmonary function related to many clinical situations. It offers services including oxygen profiling, infection and treatment, and the ability to deliver, measure, and test the pre-clinical potential of therapeutic interventions via aerosol, as well as housing of the small animals used in these studies. The PIP Core is located in the Department of Comparative Medicine (Room CG737) and is operated under the oversight of the Department of Pediatrics. To learn more about the PIP Core or to schedule an appointment go to http://www.pennstatehershey.org/web/pulmonary-core/home
- April 2015 - Dr Thomas Abraham's Shared Instrumentation Grant for a new Nikon A1 MP+ Multiphototon Microscope System was awarded. This advanced imaging instrument has deep tissue imaging and fast hybrid scanning capabilities. Congratulations to Dr. Abraham and the Imaging Core Facility!
- Thanks to the Capital Equipment Purchase Program made available by the Office of the Vice Dean for Research & Graduate Studies, the following new equipment is now available to researchers:
QuantStudio Real-Time PCR System & Digital PCR Reader are located in the Genome Sciences Core (C2705) Contact Rob Brucklacher firstname.lastname@example.org for information
14 color LSR Fortessa located in the Flow Cytometry Core (C3603) Contact Nate Sheaffer email@example.com for information
Seahorse XF96 Extracellular Flux Analyzer is located in C2705. Contact Wade Edris firstname.lastname@example.org for information.
- The Genomics Core Facility sponsored LifeTech seminars on Digital PCR and RNA SEQ - these were recorded by Mediasite broadcast, and can be viewed from your desktop - link is http://live.libraries.psu.edu/Mediasite/Play/0afb35b533cc4079b9fb0a41c09b7fa01d?catalog=348c4f44-c319-43cf-aa97-b50700fd983
- A Biacore 3000 Surface Plasmon Resonance instrument is now located in room C2705 and available for use. Please see the web page for more info www.pennstatehershey.org/web/core/surface-plasmon-resonance
- Please help us catalogue ALL resources at PSU by adding candidate resources (instruments, services, consultations, unique reagents, virus stocks, plasmids, yeast strains, etc.) to the list at https://wikispaces.psu.edu/x/V-vUB
- May 2012 - Dr. Colin Barnstable's Shared Instrumentation Grant for a new Live-Cell Confocal Microscope was funded. Congratulations Dr. Barnstable and group!
- April 2012 - Dr. Susan Hafenstein's Shared Instrumentation Grant for a new CryoEM Microscope was funded, and institutional funds were added to purchase the new system. Congratulations Dr. Hafenstein and group!