Current Residents

General Surgery Academic Year 2013/2014

Diego M. Avella, M.D.

Resident, PGY 5 (Chief)

 

Biographical Information:

Hometown: Columbia

Memberships/Societies: Resident and Associate Society of the American College of Surgeons, Association for Academic Surgery, Society for Surgery of the Alimentary Tract

Awards/Honors: Top 24 Papers. Travel Award. 23rd Annual SSAT Residents and Fellows Research Conference. Digestive Diseases Week 2008. April 2008. San Diego, CA; Best Per Review Paper. International Society of Gastrointestinal Oncology (ISGIO). September 2007. Philadelphia, PA. 

 

Education:

Medical School: Universidad El Bosque School of Medicine, Columbia

Additional Degrees: Postdoctoral Fellowship Penn State University College of Medicine,  

 

Clinical Interests:

Thoracic Surgery 

 

Research Interests:

Tumor Biology, Surgical Oncology, Thoracic Surgery 

 

Publications:

Publications:

1. Avella DM, Li G, Schell TD, Liu D, Zhang SS, Lou X, Berg A, Kimchi ET, Tagaram HR, Yang Q, Shereef S, Garcia LS, Kester M, Isom HC, Rountree CB, Staveley-O'Carroll KF. Regression of established hepatocellular carcinoma is induced by chemoimmunotherapy in an orthotopic murine model. Hepatology. 2012 Jan;55(1):141-52 Impact factor: 12.003

2. Avella DM, Kimchi ET, Donahue RN, Tagaram HR, McLaughlin PJ, Zagon IS, Staveley-O'Carroll KF. The opioid growth factor-opioid growth factor receptor axis regulates cell proliferation of human hepatocellular cancer. Am J Physiol Regul Integr Comp Physiol. 2010 Feb; 298(2):R459-66.Impact factor: 3.336

3. Tagaram HR, Divittore NA, Barth BM, Kaiser JM, Avella DM, Kimchi ET, Jiang Y, Isom HC, Kester M, Staveley-O'Carroll KF. Nanoliposomal ceramide prevents in vivo growth of hepatocellular carcinoma. Gut. 2011 May;60(5):695-701.Impact factor: 10.73

4. Avella DM, Podany A, Staveley-O'Carroll KF, Kaifi JT. Laparoscopic repair of post-esophagectomy diaphragmatic hernias using human acellular dermal matrix. Interact Cardiovasc Thorac Surg. 2011 Aug;13(2):248-9. Impact Factor: 1.112

5. Avella DM, Garcia LJ, Gusani NJ, Nikfarjam M, Shereef S, Kimchi ET, Staveley-O'Carroll KF. Human acellular dermal matrix: an innovative tool for diaphragmatic reconstruction in patients with large intra-abdominal tumors. Am J Surg. 2010 Jan; 199(1):e12-6.  Impact factor: 2.776

6. Garcia LJ, Avella DM, Hartman B, Kimchi E, Staveley-O'Carroll KF. Thoracoabdominal incision: a forgotten tool in the management of complex upper gastrointestinal complications. Am J Surg. 2009 Feb;197(2):e28-31. Impact factor: 2.776

7. Avella DM, Garcia L, Hartman B, Kimchi E, Staveley-O'Carroll K. Esophageal extension encountered during transhiatal resection of gastric or gastroesophageal tumors: attaining a negative margin. J Gastrointest Surg. 2009 Feb;13(2):368-73. Impact factor: 2.826

8. Gusani N, Avella D, Staveley-O'Carroll K, Kimchi E. Thoracoabdominal Incision: A Forgotten tool. Operative Techniques in General Surgery. 2008 June 10(2): 107-110

9. Kimchi ET, Nikfarjam M, Gusani NJ, Avella DM, Staveley-O'Carroll KF. Combined pancreaticoduodenectomy and extended right hemicolectomy: outcomes and indications. HPB (Oxford). 2009 Nov;11(7):559-64. Impact factor: 1.604

10. Nikfarjam M, Kimchi ET, Gusani NJ, Avella DM, Shereef S, Staveley-O'Carroll KF. Reduction of surgical site infections by use of pulsatile lavage irrigation after prolonged intra-abdominal surgical procedures. Am J Surg.2009 Sep;198(3):381-6. Impact factor: 2.776

11. Nikfarjam M, Sehmbey M, Kimchi ET, Gusani NJ, Shereef S, Avella DM, Staveley-O'Carroll KF. Additional organ resection combined with pancreaticoduodenectomy does not increase postoperative morbidity and mortality. J Gastrointest Surg. 2009 May;13(5):915-21. Impact factor: 2.826

12. Nikfarjam M, Shereef S, Kimchi ET, Gusani NJ, Jiang Y, Avella DM, Mahraj RP, Staveley-O'Carroll KF. Survival outcomes of patients with colorectal liver metastases following hepatic resection or ablation in the era of effective chemotherapy. Ann Surg Oncol. 2009 Jul;16(7):1860-7. Impact Factor: 4.166

13. Choudry H, Avella DM, Garcia L, Han D, Staveley-O'Carroll K, Kimchi E. Use of the left renal vein as a practical conduit in superior mesenteric vein reconstruction. J Surg Res. 2008 May 1;146(1):117-20. Impact Factor: 2.247

Presentations:

1. Avella D. MD, Garcia L. MD, Tagaram H. PhD, Shereef S. MD, Jiang Y. MD, PhD, Nikfarjam M. MD, PhD, Gusani N. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD.. Immunologic Ignorance and Tolerance, Both Play a Role in Hepatic Tumorigenesis. Society for Surgery of the Alimentary Tract (SSAT). Digestive Diseases Week 2008. May 17-22. 2008. San Diego, CA.                                                                                                                                                                                                                                                                             

2. Avella D. MD, Garcia L. MD, Shereef S. MD, Tagaram H. PhD, Jiang Y. MD, PhD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Tumor Growth in the liver depends on antigen load and immunologic ignorance. International Society of Gastrointestinal Oncology (ISGIO). Annual Congress of International Society of Gastrointestinal Oncology (ISGIO). September 28-29/2007. Philadelphia, PA. 

3. Avella D. MD, Garcia L. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Tolerance to a Tumor Associated Antigen is Dependent upon the Site of Expression and Antigenic Load. American Hepato-Pancreato-Biliary Association (AHPBA). Annual Congress of American Hepato-Pancreato-Biliary Association (AHPBA). April 19-22, 2007 Las Vegas, NV.

4. Avella D. MD, Garcia L. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Total Gastrectomy and Transhiatal Esphagectomy with Colonic Interposition for the Treatment of Large Siewert Type II Gastroesophageal Junction Tumors. Association for Academic Surgery (AAS). 2nd Annual Academic Surgical Congress. February 6-9, 2007. Phoenix, AZ.

5. Avella D. MD, Garcia L. MD, Shereef S. MD, Nikfarjam M. MD, PhD, Gusani N. MD   Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Alloderm Mesh: An Innovative Tool for Diaphragmatic Reconstruction in Patients with large retroperitoneal Sarcomas. Association for Academic Surgery (AAS).  3rd Annual Academic Surgical Congress. February 12-15, 2008. Huntington Beach, CA.

6. Tagaram H and  Rolin O, Avella D, Garcia L, Kimchi E, Schell T, Tevethia S, Staveley-O'Carroll K.  CD40 Ligation Enhances Na├»ve Tumor Antigen-Specific CD8+ T cell Responses in Spontaneous Osteosarcoma Model. American Association of Immunologists (AAI). 95th Annual Meeting of AAI Immunology. March 12-16 2008. San Diego, CA.

7. Avella D. MD, Garcia L. MD, Tagaram H. PhD, Shereef S. MD, Jiang Y. MD, PhD, Nikfarjam M. MD, PhD, Gusani N. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Immunologic Ignorance and Tolerance, Both Play a Role in Hepatic Tumorigenesis. Society for Surgery of the Alimentary Tract (SSAT). Digestive Diseases Week 2008. May 17-22. 2008. San Diego, CA. 

8. Avella D. MD, Tagaram H. PhD, Sehmbey M, Garcia L. MD, Shereef S. MD, Kimchi E. MD, Zagon I. PhD, McLaughlin P. SD, Staveley-O'Carroll K. MD, PhD. Opioid Growth Factor Mediated Inhibition of Hepatic Carcinoma in vitro. Annual Congress of the American Hepato-Pancreato-Biliary Association (AHPBA). March 27-30, 2008. Fort Lauderdale. FL.

9. Shereef S., Avella D., MD, Garcia L., MD, Tagaram H., PhD, Gusani N, MD, Nikfarjam M., MD PhD, Kimchi E., MD, Staveley-O'Carroll K., MD, PhD. Magnetic Resonance Imaging is a powerful tool for characterizing the impact of Radiofrequency Ablation in a Murine model of Spontaneous Hepatocellular Cancer. Annual Congress of the American Hepato-Pancreato-Biliary Association (AHPBA). March 27-30, 2008. Fort Lauderdale. FL.

10.  Garcia L. MD, Avella D. MD, Shereef S. MD, Tagaram H. PhD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. MTD2 Mice Provide an Excellent Model for in vivo Adoptive Transfer Studies to Evaluate the Tumor Antigen Specific T cell Response to Hepatocellular Cancer. Association for Academic Surgery (AAS). 3rd Annual Academic Surgical Congress. February 12-15, 2008. Huntington Beach, CA.

11.  Avella D. MD, Garcia L. MD, Shereef S. MD, Tagaram H. PhD, Jiang Y. MD, PhD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Tumor Growth in the liver depends on antigen load and immunologic ignorance. Annual Congress of the International Society of Gastrointestinal Oncology (ISGIO). September 27-29, 2007. Philadelphia, PA

12.  Garcia L. MD, Avella D. MD, Shereef S. MD, Tagaram H. PhD, Mosher T. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Contrast Enhanced Magnetic Resonance Imaging: A Reliable Method to Evaluate Tumor Progression/Regression in a Murine Model of Hepatocellular cancer. Annual Congress of the International Society of Gastrointestinal Oncology (ISGIO). September 27-29, 2007. Philadelphia, PA

13.  Avella D. MD, Garcia L. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Tolerance to a Tumor Associated Antigen is Dependent upon the Site of Expression and Antigenic Load. Annual Congress of the American Hepato-Pancreato-Biliary Association (AHPBA). April 19-22, 2007 Las Vegas, NV.

14.  Garcia L. MD and  Rolin O, Avella D. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Liver Sinusoidal Endothelial Cells: Phenotypic Characterization by electron Microscopy. Annual Congress of the American Hepato-Pancreato-Biliary Association (AHPBA). April 19-22, 2007. Las Vegas, NV.

15.  Avella D. MD, Garcia L. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Total Gastrectomy and Transhiatal Esophagectomy with Colonic Interposition for the Treatment of Large Siewert Type II Gastroesophageal Junction Tumors. Association for Academic Surgery (AAS). 2nd Annual Academic Surgical Congress. February 6-9, 2007. Phoenix, AZ.

16.  Garcia L. MD, Avella D. MD, Kimchi E. MD, Staveley-O'Carroll K. MD, PhD. Thoracoabdominal incision: A forgotten tool in the management of complex Upper Gastrointestinal Complications. Association for Academic Surgery (AAS). 2nd Annual Academic Surgical Congress. February 6-9, 2007. Phoenix, AZ.  

 

 

 

Diego M. Avella, M.D.

 

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