Research Forum
March 1, 2013
The Graduate Student Research Forum is sponsored by the Graduate Student Association of the Penn State College of Medicine. The primary goal of the Forum is to promote interaction and the exchange of ideas between students and faculty. The Forum introduces students to the format generally used at scientific meetings, and it provides an opportunity to recognize excellence in graduate research at Penn State University College of Medicine.
The 2013 Forum Speaker is:
Donald Brian Katz , Ph.D.
Associate Professor
Brandeis University
Boston, Massachusetts
Forum Schedule of Events
Thursday - February 28
4:00 PM - 5:00 PM Research Seminar (Lecture Room A)
"The Neural Dynamics of Taste Perception"
Donald Brian Katz , Ph.D.
Associate Professor
Brandeis University
Boston, Massachusetts
Friday - March 1
8:00 AM - 8:45 AM - Breakfast/Registration (hallways outside C3621)
8:45 AM - 9:00 AM - Opening Remarks/GSA Comments (Lecture Room A)
Brandeis University
Boston, Massachusetts
1:30 PM - 3:00 PM - Oral Presentations 2 (Lecture Room A)
3:00 PM - 4:45 PM - Poster Presentations 2 (C3621)
6:30 PM - midnight - Forum Reception (University Conference Center)
Student Presenter/Faculty Evaluator Schedule
Poster Presentations | ||||||
Name | Graduate School Year | Graduate Program | Abstract Title | Time | Evaluator | Evaluator |
| Allison Fries | Second | Biomedical Sciences | Chronic homotypic stress may affect GI functions via upregulation of oxytocin within PVN-DVC neurocircuits | AM - 1 | Victor Canfield | Raghu Sinha |
| Breanna Rice | Second | Biomedical Sciences | Interaction of Chromatin-Bound Host Factors with the Retroviral Gag Protein | AM - 2 | Ralph L Keil | Raghu K. Tadagavadi |
| Caesar Imperio | Third | Neuroscience | Exposure to environmental enrichment attenuates the motivation to work for heroin in adult male rats and diminishes relapse-like behaviors after drug abstinence | AM - 3 | Raghu Sinha | R. Alberto Travagli |
| Christine G. Skibinski | Fourth | Biochemistry and Molecular Biology | Plasma Proteomic Changes Induced by Effective Chemopreventive Raios of n-3:n-6 Fatty Acids Against MNU-Induced Mammary Carcinogenesis in the Rat | AM - 4 | Lan Kong | Sang Lee |
| Dai Liu | Fourth | Molecular Medicine | Sunitinib inhibits hepatocellular carcinoma (HCC) tumor growth and mediates antitumor immunity through modulating regulatory T cells via TGF-b signaling | AM - 5 | Ira Ropson | Joerg Roesgen |
| Dominique Leitner | Fourth | Neuroscience | Semaphorin4A is Elevated in Fatal Murine Cerebral Malaria and is Pro-Apoptotic to Oligodendrocyte Progenitors | AM - 6 | Andras Hajnal | Zissis Chroneos |
| Dustin R. Masser | Second | Biomedical Sciences | Targeted DNA Methylation Analysis Using Bisulfite Conversion and Ultra-deep Next Generation Sequencing | AM - 7 | Zissis Chroneos | Thomas Spratt |
| Elizabeth M Colechio | Third | Neuroscience | Using Taste Reactivity to Track the Development of Affective Responses to Drug Cues | AM - 8 | Ira Ropson | Sang Lee |
| Gregory Kardos | Fourth | Genetics | Targeting Ribosomal Proteins for Therapeutic Inhibition of Melanoma Growth | AM - 9 | Robin Taylor Wilson | Ian Simpson |
| Izel Tekin | Third | Pharmacology | The V81M(G241A) Polymorphism of Human Tyrosine Hydroxylase Increases the Michaelis-Menten Constant for Tyrosine and Increases Progression of Parkinson's Disease | AM -10 | Cara-Lynne Scheungrund | Gregory Yochum |
| Jennifer Biryukov | Fourth | Microbiology and Immunology | Co-Habitation: What Happens when Two Human Papillomavirus Types Infect Together? | AM - 11 | Sue Grigson | David Feith |
| Jessica Immonen | Fourth | Anatomy | Topical Treatment with the Opioid Antagonist Naltrexone Facilitates Closure of Full-thickness Wounds in Diabetic Rats by Accelerating Angiogenesis | AM - 12 | Gordon Kauffman | Andras Hajnal |
| Katrina Heyrana | Third | Cell and Molecular Biology | Charged Residues in Surface-Exposed Capsid Loops Mediate Immature Assembly of Infection-competent Retroviruses | AM - 13 | Leo R. Fitzpatrick | Jill Smith |
| Lauren A. Weiler | Third | Microbiology and Immunology | Role of myeloid cell subsets in the immune response to ectromelia virus | AM - 14 | Gregory Yochum | Leslie Parent |
| Manmeet Raval | Second | Physiology | Functional role of specific regions of the tail domain of Myosin IIIA in actin bundle based motility | AM - 15 | Cara-Lynne Scheungrund | Leslie Parent |
| Megan Young | Fourth | Pharmacology | Autophagy protects the cell from vacuolization and cell death induced by the amine-containing sphingosine kinase 1 inhibitor, SK1-I | AM - 16 | Ian Simpson | Neil Christensen |
| Nancy Porterfield | Third | Cell and Molecular Biology | Growth of Triple Negative Human Breast Cancer Cells is regulated by the OGF-OGFr Axis | AM - 17 | Thomas Spratt | Neil Christensen |
| Nicolle Krebs | Second | Public Health Sciences | Influenza Vaccination Status among Pregnant Women: Effects of Maternal Attitudes, Knowledge, and Healthcare Provider Recommendation | AM - 18 | Robin Taylor Wilson | Lan Kong |
| Rahul Dewal | Fifth | Bioengineering | A synergistic passive and active shimming system to optimize B0 field homogeneity in micro MR imaging | AM - 19 | Dhimant Desai | Lan Kong |
| Shang-Min Zhang | Fifth | Biochemistry and Molecular Biology | Effect of alcohol on tobacco on DB[a,l]P, an environmental pollutant and a tobacco smoke constituent, on DNA adduct formation in mouse oral tissues | AM - 20 | Gordon Kauffman | David Feith |
| Tiaosi Xing | Second | Anatomy | Role of 3-phosphoinositide-dependent protein kinase-1 in Rod photoreceptor differentiation | AM - 21 | Dhimant Desai | Leo R. Fitzpatrick |
| Wint Nandar | Fifth | Neuroscience | The H63D HFE Gene Variant Accelerates Disease Progression in Amyotrophic Lateral Sclerosis (ALS) | AM - 22 | Sue Grigson | Raghu Sinha |
| Xiaowei William Su | Second | Molecular Medicine | H63D HFE mutation contributes to ALS pathogenesis via mitochondria and alters disease duration | AM - 23 | Ralph L Keil | Raghu K. Tadagavadi |
| Zainul S. Hasanali | Second | Molecular Medicine | Epigenetic Modulation of CD30 Gene Expression in Alemtuzumab Resistant T-Cell PLL: Rationale and Efficacy of Brentuximab Vedotin | AM - 24 | R. Alberto Travagli | Victor Canfield |
| Brittany Ebersole | Fourth | IBIOS/Chemical Biology | Palmitoylation of the dopamine D2 receptor and its effect on trafficking | PM - 1 | Kirsteen Browning | Lisa Shantz |
| Cara Bicking Kinsey | Fifth | Nursing | Validity and reliability of a modified version of the Postpartum Bonding Questionnaire | PM - 2 | Kirsteen Browning | Jill Smith |
| Christopher B. Jenney | Third | Neuroscience | Omega-3 Fatty Acid Deficiency Leads to Increased Cocaine Addiction-Like Behavior in Rats | PM - 3 | Charles Lang | Rebecca Craven |
| Cody Weston | Third | Neuroscience | Treatment with Ferric Iron Down regulates E-Cadherin in a Model of Breast Cancer in vitro and May Promote Epithelial to Mesenchymal Transition | PM - 4 | Sarah Bronson | Rebecca Craven |
| Deepkamal N. Karelia | Second | Molecular Toxicology | NISC-6, a naphthalimide analog, suppresses pancreatic cancer cell growth through activation of death receptor 5 | PM - 5 | Sang Lee | Victor Canfield |
| Emily M. Swartz | Third | Anatomy | Nitric oxide synthase, cholecystokinin, and TRPV1 mRNA levels in the upper gastrointestinal tract of rats following experimental spinal cord injury | PM - 6 | Stephanie M. Patton | Thomas C. Pritchard |
| Francis R LeBlanc | Fourth | Molecular Medicine | Targeting sphingosine kinase 1 in Natural Killer Large Granular Lymphocyte Leukemia | PM - 7 | Sang Lee | Alistair Barber |
| Gihan Jayasuriya | Fourth | Cell and Molecular Biology | Dronedarone allosterically modulates muscarinic acetylcholine receptors | PM - 8 | Charles Lang | Fang Tian |
| Hyunwook Lee | Third | Microbiology and Immunology | Structural study of the Enterovirus 71 complexed with Fab reveals the neutralization mechanisms of an antibody | PM - 9 | A. B. Madhan Kumar | Ralph L Keil |
| Jacob Hornick | Third | Biochemistry and Molecular Biology | Mammalian GPCR Expression and Pharmacological Studies in Saccharomyces cerevisiae | PM - 10 | Alistair Barber | Jill Smith |
| Kari Duck | Fourth | IBIOS/Cell and Developmental Biology | A novel model for brain iron uptake: Introducing the concept of regulation | PM - 11 | Raghavendra Gowda | Neil Christensen |
| Kristin L. Shingler | Second | Microbiology and Immunology | The Enterovirus 71 A-Particle Forms a Gateway to Allow Genome Release: A CryoEM Study of Picornavirus Uncoating | PM - 12 | Pooja Chadha | Victor Canfield |
| Lindsey Organtini | Third | Microbiology and Immunology | Receptor binding to Coxsackievirus B3 catalyzes conformational changes resulting in A-particle | PM - 13 | Pooja Chadha | R. Alberto Travagli |
| Loren D. Archibeque | First | Public Health Sciences | Differences in Vitamin D Metabolites due to the Ancestral genetics of CYP3A43 and CYP24P-262 | PM - 14 | Dr. Pat McLaughlin | Thomas C. Pritchard |
| Matthew R. England | Fifth | Microbiology and Immunology | Regulation of Retrovirus Capsid Dimerization by Hydrophobic Residues in the C-Terminal Domain | PM - 15 | Pooja Chadha | Raghu K. Tadagavadi |
| Matthew S. Stake | Fourth | Cell and Molecular Biology | The Role of Transportin 3 in Rous Sarcoma Virus Assembly | PM - 16 | Sarah Bronson | Amanda Snyder |
| Min Pang | Fifth | IBIOS/Chemical Biology | The Down-regulation of Ferritin Heavy Chain as an Adjuvant Therapy in Human Glioma | PM - 17 | Jill Smith | Ralph L Keil |
| Nicholas W. Sterling | Second | Public Health Sciences | Shape analysis of the striatum in Parkinson's disease | PM - 18 | Gordon Kauffman | Rosalyn Irby |
| Peter Govey | Fifth | Bioengineering | Integrative Transcriptomic and Proteomic Analysis of Osteocytic Cells Exposed to Fluid Flow | PM - 19 | Raghu K. Tadagavadi | A.B.Madhan Kumar |
| Scott A. Jones | Fifth | Microbiology and Immunology | Mapping Hepatitis B Virus Polymerase Sequences Required for Protein Priming | PM - 20 | Neil Christensen | Pat McLaughlin |
| Stephanie Bywaters | Second | Microbiology and Immunology | Analysis of HPV: Antibody Neutralizing Structures | PM - 21 | R. Alberto Travagli | Raghavendra Gowda |
| Steven Steinway | Second | Molecular Medicine | Network modeling reveals critical mechanisms driving epithelial-to-mesenchymal transition in liver cancer invasion and metastasis | PM - 22 | Rosalyn Irby | Amanda Snyder |
| Vasudha Bharatula | Second | Biomedical Sciences | PKA and SNF-1 regulate nucleocytoplasmic shuttling of Msn2 under conditions of oxidative stress | PM - 23 | Stephanie M. Patton | Lisa Shantz |
| Vijaykumar Kale | Third | Molecular Toxicology | DJ4, a Novel Rho Kinase Inhibitor, Potently Inhibits Migration of Lung Cancer Cells | PM - 24 | Raghavendra Gowda | Amanda Snyder |
| Zachary Reagan | Second | Anatomy | The Effect of Bicuculline Methiodide on Gastric Tone and Motility in Perinatal High Fat Fed Animals | PM - 25 | Fang Tian | Gordon Kauffman |
Oral Presentations | ||||||
Name | Graduate School Year | Graduate Program | Abstract Title | Time | Evaluator | Evaluator |
| Andrew R. Kelleher | Fourth | Physiology | The repressors of mTORC1 signaling REDD1/2 are rapidly induced and activation of p70S6K1 by a nutrient stimulus is defective in skeletal muscle of an immobilized rat hindlimb | AM-1 | Gordon Kauffman | Gregory Yochum |
| Colleen Van Kirk | Fifth | Pharmacology | Induction of major histocompatibility complex I in rodent models of human CNS aging: implications for age-related synaptic dysfunction | AM-2 | David Feith | Leslie Parent |
| Kristen D. Yetming | Fourth | Microbiology and Immunology | Latency-Associated Function of the Epstein-Barr Virus BHLF1 Gene | AM -3 | Ralph L Keil | Leslie Parent |
| Matthew Dziublenski | Fourth | Biochemistry and Molecular Biology | Post-Transcriptional Regulation of the Inflammatory Cytokine IL-13 by the RNA-binding Protein TTP | AM- 4 | Zissis Chroneos | R. Alberto Travagli |
| Rebecca J. Kaddis | Fourth | Cell and Molecular Biology | Straight to the Source: Packaging of Genomic RNA by RSV Gag | AM-5 | Joerg Roesgen | Kirsteen N Browning |
| Ronaldo P. Panganiban | First | Biomedical Sciences | Differential miRNA Expression in Asthma and the Role of miR-1248 in the Regulation of IL-5 | AM-6 | Gregory Yochum | David Feith |
| Travis D'Cruz | Fifth | Neuroscience | Diabetes and Post-Translational Glycosylation of Synaptophysin in the Retina | AM-7 | Robin Taylor Wilson | Thomas Spratt |
| Lynnsay A. Marsan | Fourth | Neuroscience | Implications of the A112G single nucleotide polymorphism on the mu-opioid receptor-mediated modulation of HPA axis activation | AM- 8 | Raghu K. Tadagavadi | Rebecca Craven |
| Allison Cleary | Fourth | Cell and Molecular Biology | Elucidating the Cell Non-Autonomous Effects of Oncogene Expression in Chimeric Mammary Organoid Culture | PM-1 | Pooja Chadha | A. B. Madhan Kumar |
| Amanda E. Troy | Third | Anatomy | High fat diet decreases glucose-dependent modulation of 5-HT responses in gastrointestinal vagal afferent neurons | PM-2 | Ian Simpson | Stephanie M. Patton |
| Douglas Dluzen | Fifth | Genetics | miR-491-3p regulation of the UDP-glucuronosyltransferase (UGT) 1A gene family | PM-3 | Sarah Bronson | Rosalyn Irby |
| Gregory Berry | Fourth | Microbiology and Immunology | Mechanisms of Idd9-mediated Type 1 Diabetes Susceptibility | PM-4 | Ralph L Keil | Sarah Bronson |
| Megha Vasavada | Fourth | Neuroscience | Primary Olfactory Cortex is Involved in Alzheimer's Disease | PM-5 | Rosalyn Irby | A.B.Madhan Kumar |
| Omer Faruk Kuzu | Third | Genetics | Leelamine: Targeting the "suicide bags" of the cells | PM-6 | Rebecca Craven | Alistair Barber |
| Su-Fern Tan | Fourth | Molecular Medicine | Acid ceramidase promotes Acute Myeloid Leukemia survival through Mcl-1 upregulation | PM-7 | Fang Tian | Ralph L Keil |
Donald Brian Katz, Ph.D.
Associate Professor
Brandeis University
Boston, Massachusetts
Research Summary
Professor Katz's studies the neural bases of learning. His current research examines the ways in which interactions among simultaneously recorded ensembles of single neurons underlie both the within-trial identification of taste stimuli and between-trial plasticity related to taste learning.
Publications
Caras M., MacKenzie K. J., Rodwin, B., Katz, D. B. (2008). Investigating the motivational mechanism of altered saline consumption following 5-HT1A manipulation. Behavioral Neuroscience, in press.
Grossman S. A., Fontanini A. F., Wieskopf J. S., Katz, D. B. (2008). Learning-related plasticity of temporal coding in simultaneously-recorded amygdala-cortical ensembles. Journal of Neuroscience, 28(11), 2864-2873
Verhagen, J. V. Katz, D. B. (2008). More time to taste. Focus on "Variability in responses and temporal coding of tastants of similar quality in the nucleus of the solitary tract of the rat". Journal of Neurophysiology, 99 413-414
Fontanini A., Grossman S. A., Revill B. R., Katz, D. B. (2008). Cortical ensembles in taste coding. In Olfaction and Taste (Firestein S & Beauchamp GK, eds), San Diego: Academic Press, pp 329-338
Lemon, C. H., Katz, D. B. (2007). The neural processing of taste. BMC Neuroscience, 8(Supp. 3), S5.
Jones L. M., Fontanini A., Sadacca B. F., Miller P., Katz, D. B. (2007). Natural stimuli evoke dynamic sequences of states in cortical ensembles. PNAS, 104, 18772-18777.
Wang J. Y-Y., Fontanini A., Katz, D. B. (2006). Temporary basolateral amygdala lesions disrupt acquisition of socially transmitted food preferences in rats. Learning & Memory, 13, 794-800.
Jones L. M., Fontanini A., Katz, D. B. (2006). Gustatory processing: a dynamic systems approach. Current Opinion in Neurobiology, 16(4), 420-428.
Fontanini A., Katz, D. B. (2006). State-dependent modulation of time-varying gustatory responses. Journal of Neurophysiology, 96(6), 3183-3193. (See commentary).
Stone M. E., Grimes B. S., Katz, D. B. (2005). Hippocampal inactivation enhances taste learning. Learning & Memory, 12, 579-586. (See commentary).
Fontanini A., Katz, D. B. (2005). 7-12 Hz activity in rat gustatory cortex reflects disengagement form a fluid self-administration task. Journal of Neurophysiology, 93(5), 2832-2840. (See commentary).
Katz, D. B. (2003). Making time with taste. Focus on "Taste response variability and temporal coding in the nucleus of the solitary tract of the rat". Journal of Neurophysiology, 90(3) 1375-1376.
Katz, D. B., Nicolelis, M. A. L., & Simon, S. A. (2002). Gustatory processing is dynamic and distributed. Current Opinion in Neurobiology, 12, 448-454.
Katz, D. B.,Simon, S. A., & Nicolelis, M. A. L. (2001). Dynamic and multimodal responses of gustatory cortical neurons in awake rats. Journal of Neuroscience, 21(12), 4478-4489.
Katz, D. B., Simon, S. A., & Nicolelis, M. A. L. (2001). Electrophysiological studies of gustation in awake rats. In Nicolelis, M. A. L. & Simon, S. A., Methods in Chemosensory Research (pp339-357). Boca Raton, FL: CRC Press.
Katz, D. B., Nicolelis, M. A. L., & Simon, S. A. (2000). Nutrient Tasting and Signaling Mechanisms in the Gut IV. There is more to taste than meets the tongue. American Journal of Physiology, 12, 448-454.
This information was obtained from the following websites:
- Presenter List (Oral and Poster presentation)
- Evaluator Schedule
- Abstract Formatting Instructions
- Example of Abstract
- Poster Presentation Directions
- Oral Presentation Directions
- Reception Details
Abstract submission
- Visit the Abstract Submission Page
- Deadline for Forum 2013 abstract submission is January 7, 2013