Class Year: M3
Undergraduate Education: BS/06 Chemistry/Penn State U
Research Interest: Understanding the mechanisms of low-dose irradiation that promote tumor-targeting CD8+ T cell responses
Advisor: Todd Schell, PhD
Graduate Program: Cell & Molecular Biology
Description: We are investigating the role of cytotoxic T cells in the treatment of cancer. Tumors create an immunosuppressive, toleragenic microenvironment, and we are researching means of overcoming suppression of the T cell response and the development of T cell tolerance to "self" tumor antigens. Specifically, I will be looking at the role of lymphodepleting radiation treatment and it's effects on the tumor microenvironment and cytotoxic T cell response.
Penn State College of Medicine Graduate Research Forum, Hershey, PA (poster)
Translational Research Cancer Center Consortium, Seven Springs, PA
Cozza EM, Cooper TK, Budgeon LR, Christensen ND, Schell TD (2014) Protection from tumor recurrence following adoptive immunotherapy varies with host conditioning regimen despite initial regression of autochthonous murine brain tumors Cancer Immunology, Immunotherapy (accepted)
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