Student Directory

Cody Weston

Cody Weston

Class Year: M3

Department/Institute/Center(s):

  • M.D./Ph.D. Program

Biographical Information:

Hometown: Lansing, MI

Education:

Undergraduate Education:  BS/08 Physiology;Psychology/Michigan State U

Research Interests:



Advisor: James Connor, PhD
Graduate Program: Neuroscience

Thesis: "Understanding the role of HFE Polymorphism in Cancer"

Research Interest: The relationship between iron metabolism and cancer progression

Description:  To better understand cancer biology and the interplay between tumor progression and iron, I am making use of a variety of in vitro and in vivo models. In brief, I am studying the effects of iron loading, iron chelation, HFE (a protein involved in iron handling that is commonly mutated in the population) status, and H-ferritin deficiency. My outcomes of interest include whole-animal metastatic spread (assessed using IVIS luciferase imaging), cell viability and DNA turnover in culture, and chemotherapeutic sensitivity. 
 
Meeting Presentations
  • 2007
    Michigan State University Undergraduate Research & Arts Forum, MI

  • 2013
    International BioIron Society, London, UK

     

 

 

Publications:

Weston CL, Glantz MJ, Connor JR (2011) Detection of cancer cells in the cerebrospinal fluid:  current methods and future directions Fluids Barriers CNS 8(1):14  PMCID:  PMC3059292

Zalatimo O, Zoccoli CM, Patel A, Weston CL, Glantz M (2013) Impact of genetic targets on primary brain tumor therapy:  what's ready for prime time? Adv Exp Med Biol 779:267-89  PMCID:  (no number)

Weston C, Connor JR (2014) Evidence for the influence of the iron regulatory MHC class I molecule HFE on tumor progression in experimental models and clinical populations Translational Oncogenomics (accepted)

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