Allogeneic Transplant

Allogeneic means “from another person”. Stem cells for this type of transplant are obtained from a variety of sources:

• Matched related donors (MRD) are usually siblings whose stem cells are most similar to those of the patient.
• Some patients will receive stem cells from a partially matched related donor, such as a parent.
• The National Donor Registry provides information to find a matched unrelated donor (MUD) from a pool of adults who donate their stem cells for transplantation.
• Umbilical cord blood can also be used and can be located through National Registries.

Penn State Hershey Children’s Hospital Transplant team performs allogeneic transplants for diseases such as:

• Acute lymphoblastic leukemia (ALL)
• Acute myelogenous leukemia (AML)
• Chronic myelogenous leukemia (CML)
• Myelodysplastic syndrome (MDS)
• Juvenile myelomonocytic leukemia (JMMoL)
• Lymphoma
• Aplastic anemia
• Immunodeficiency Disorders 
• Metabolic disorders
• Hemoglobin disorders such as sickle cell anemia and Beta-thalassemia