Allogeneic means “from another person”. Stem cells for this type of transplant are obtained from a variety of sources:
- Matched related donors (MRD) are usually siblings whose stem cells are most similar to those of the patient.
- Some patients will receive stem cells from a partially matched related donor, such as a parent.
- The National Donor Registry provides information to find a matched unrelated donor (MUD) from a pool of adults who donate their stem cells for transplantation.
- Umbilical cord blood can also be used and can be located through National Registries.
Penn State Hershey Children’s Hospital Transplant team performs allogeneic transplants for diseases such as:
- Acute lymphoblastic leukemia (ALL)
- Acute myelogenous leukemia (AML)
- Chronic myelogenous leukemia (CML)
- Myelodysplastic syndrome (MDS)
- Juvenile myelomonocytic leukemia (JMMoL)
- Aplastic anemia
- Immunodeficiency Disorders
- Metabolic disorders
- Hemoglobin disorders such as sickle cell anemia and Beta-thalassemia