Radiology - Research Overview

Penn State Hershey Radiology has a long history of commitment to imaging research. Historically the primary focus has been NMR/MRI research with installation of one of the first in vivo multi-nuclear NMR spectroscopy systems in 1983, and development of the Penn State Center for NMR Research in 1991. The focal point of this facility is the Center's 3.0 T Bruker S-300 Scanner installed in 1991, which is also capable of multinuclear NMR spectroscopy. This system was one of the first 3.0 T systems to be installed in the world. Since 1991, the Center has become one of the premier sites for ultra-high field MRI research recently having refunding of a $6.9 million NIH Bioengineering Partnership Grant to evaluate ultra-high MRI in 2007. Recent additions to the Center include a 7.0 T Bruker horizontal bore system for small animal imaging/multi-nuclear spectroscopy, and major upgrades to the Bruker 3.0 T system. In addition the Department installed one of the first Philips 3.0 T MRI clinical scanners in 2004.

Our MRI Core facility provides facilities for human research. This facility includes a new Siemens 3.0 T Trio MRI scanner, full fMRI capability, advanced cardiovascular, breast and orthopedic imaging capability.   Major research interests include modeling and simulation of ultra-high field radio-frequency and static field behavior in MRI, pulse sequence development for fMRI and ultra-high field MRI applications, olfactory functional MRI (fMRI), and quantitative imaging for evaluation of in vivo cartilage biomechanics and early structural degeneration. Radiology researchers have a long history of collaboration with investigators at Penn State as well as numerous outside institutions. Currently, the Center serves as the primary research facility for 3.5 faculty members of the Department of Radiology.

Timothy J. Mosher, M.D.
Associate Professor Radiology and Orthopaedics
Vice Chair for Clinical Radiology Research
Chief, Musculoskeletal Imaging and MRI