Principal Investigator: James M. Leaming, MD, Department of Emergency Medicine
coPrincipal Investigator: Thomas Terndrup, MD, Department of Emergency Medicine
Investigator: Heidi Frankel, MD, Department of Surgery
Investigator: Philip Villanueva, MD, Department of Neurosurgery
Investigator: Claire Flaherty-Craig, PhD, Department of Neurology
ProTECT is a national research study evaluating the use of a hormone during a traumatic brain injury. Penn State Hershey Medical Center is one of several academic medical centers nationwide participating in this study. This study uses progesterone, a steroidal hormone found naturally in the body, to limit the damage caused during brain injury. There is currently no drug treatment for traumatic brain injury; instead doctors attempt to control blood pressure and oxygen levels to minimize damage.
This is an exception from informed consent study (see below for more information).
People who are 18 years or older with a blunt closed head injury, with moderate to severe brain injury, and who can start the study medicine within four hours from the time of injury
Who is not eligible to participate?
Those under age 18
Those allergic to eggs
Women who have breast cancer or other cancers of the female organs.